scriptnawer.blogg.se - Squish ball

The specific elastance ( K) is the slope of the curve in its linear portion. Relationship between stress and strain in healthy, ARDS and fibrotic lungs. The review also discusses the practical management of AE-ILD patients discussing illustrative clinical cases.Īcute respiratory distress syndrome Interstitial lung diseases Mechanical ventilation Respiratory failure Ventilator-induced lung injury. The role of positive end-expiratory pressure is discussed, proposing a "lung resting strategy" as opposed to the "open lung approach".

The purpose of this review is to analyze the effects of mechanical ventilation in AE-ILD and to increase the knowledge on the characteristics of fibrotic lung during artificial ventilation, introducing the concept of "squishy ball lung". Due to the severe impairment of the respiratory mechanics, the fibrotic lung is at high risk of developing ventilator-induced lung injury, regardless of the lung fibrosis etiology. ventilation is the cornerstone of treatment of patients with the acute respiratory distress syndrome (ARDS) however, no studies have yet established the best ventilatory strategy to adopt when patients with acute exacerbation of interstitial lung disease (AE-ILD) are admitted to the intensive care unit. 11 Ospedale Policlinico San Martino, IRCCS per l'Oncologia e le Neuroscienze, Genoa, Italy.

10 Dipartimento di Scienze Chirurgiche e Diagnostiche Integrate, Università degli Studi di Genova, Genoa, Italy.

9 Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB), Brussels, Belgium.

8 Intensive Care Unit Department, University Hospital Brussels (UZB), Jette, Belgium.

7 Ospedale Policlinico San Martino, IRCCS per l'Oncologia e le Neuroscienze, Genoa, Italy.

6 Dipartimento di Scienze Chirurgiche e Diagnostiche Integrate, Università degli Studi di Genova, Genoa, Italy.

5 Respiratory Unit, University of Milano Bicocca, S.

4 Respiratory Diseases Unit, University of Padua, Padua, Italy.

3 Pathologic Anatomy Unit, Azienda USL Ravenna, Ravenna, Rimini, Italy.

2 Clinical and Experimental Medicine PhD Program, University of Modena Reggio Emilia, Modena, Italy.

1 Respiratory Diseases Unit, Department of Medical and Surgical Sciences, University Hospital of Modena and Center for Rare Lung Diseases, University of Modena Reggio Emilia, Modena, Italy.